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Literature summary for 4.6.1.1 extracted from

  • Bosier, B.; Hermans, E.; Lambert, D.M.
    Concomitant activation of adenylyl cyclase suppresses the opposite influences of CB(1) cannabinoid receptor agonists on tyrosine hydroxylase expression (2009), Biochem. Pharmacol., 77, 216-227.
    View publication on PubMed
Search for more literature for 4.6.1.1

Activating Compound

Activating Compound Comment Organism Structure
forskolin strong activation Mus musculus
stimulating G protein Galphai subunits contribute to the reduction of adenylyl cyclase activity after either forskolin or GalphaS activation Mus musculus

Inhibitors

Inhibitors Comment Organism Structure
inhibitory G protein Galphai subunits contribute to the reduction of adenylyl cyclase activity after either forskolin or GalphaS activation Mus musculus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP Mus musculus enzyme regulation in cAMP signalling, overview 3',5'-cyclic-AMP + diphosphate
-
 ?
ATP Mus musculus C57BL/6 enzyme regulation in cAMP signalling, overview 3',5'-cyclic-AMP + diphosphate
-
 ?
additional information Mus musculus concomitant activation of adenylyl cyclase suppresses the opposite influences of CB1 cannabinoid receptor agonists on tyrosine hydroxylase expression, overview ?
-
 ?
additional information Mus musculus C57BL/6 concomitant activation of adenylyl cyclase suppresses the opposite influences of CB1 cannabinoid receptor agonists on tyrosine hydroxylase expression, overview ?
-
 ?

Organism

Organism UniProt Comment Textmining
Mus musculus
-
 C57BL/6 mice
-
Mus musculus C57BL/6
-
 C57BL/6 mice
-

Source Tissue

Source Tissue Comment Organism Textmining
N1E-115 cell
-
 Mus musculus
-
neuroblastoma cell
-
 Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP
-
 Mus musculus 3',5'-cyclic-AMP + diphosphate
-
 ?
ATP enzyme regulation in cAMP signalling, overview Mus musculus 3',5'-cyclic-AMP + diphosphate
-
 ?
ATP
-
 Mus musculus C57BL/6 3',5'-cyclic-AMP + diphosphate
-
 ?
ATP enzyme regulation in cAMP signalling, overview Mus musculus C57BL/6 3',5'-cyclic-AMP + diphosphate
-
 ?
additional information concomitant activation of adenylyl cyclase suppresses the opposite influences of CB1 cannabinoid receptor agonists on tyrosine hydroxylase expression, overview Mus musculus ?
-
 ?
additional information concomitant activation of adenylyl cyclase suppresses the opposite influences of CB1 cannabinoid receptor agonists on tyrosine hydroxylase expression, overview Mus musculus C57BL/6 ?
-
 ?