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Literature summary for 4.6.1.1 extracted from

  • Lee, C.B.; Koh, H.C.
    Modification of the cardiovascular response of posterior hypothalamic adenosine A(2A) receptor stimulation by adenylate cyclase and KATP channel blockade in anesthetized rats (2009), Auton. Neurosci., 146, 70-75.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
MDL-12,330A
-
Rattus norvegicus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP Rattus norvegicus the enzyme modulates the cardiovascular response of posterior hypothalamic adenosine A2A receptor stimulation, adenylate cyclase, but not guanylate cyclase, mediates the depressor and bradycardiac actions of adenosine A2A receptors, overview 3',5'-cyclic-AMP + diphosphate
-
?

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
male sprague-dawley rats
-

Source Tissue

Source Tissue Comment Organism Textmining
brain
-
Rattus norvegicus
-
hypothalamus posterior Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP
-
Rattus norvegicus 3',5'-cyclic-AMP + diphosphate
-
?
ATP the enzyme modulates the cardiovascular response of posterior hypothalamic adenosine A2A receptor stimulation, adenylate cyclase, but not guanylate cyclase, mediates the depressor and bradycardiac actions of adenosine A2A receptors, overview Rattus norvegicus 3',5'-cyclic-AMP + diphosphate
-
?