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Literature summary for 4.6.1.1 extracted from

  • Spangler, C.M.; Spangler, C.; Goettle, M.; Shen, Y.; Tang, W.J.; Seifert, R.; Schaeferling, M.
    A fluorimetric assay for real-time monitoring of adenylyl cyclase activity based on terbium norfloxacin (2008), Anal. Biochem., 381, 86-93.
    View publication on PubMed
Search for more literature for 4.6.1.1

Activating Compound

Activating Compound Comment Organism Structure
Calmodulin required for activity Bacillus anthracis

Metals/Ions

Metals/Ions Comment Organism Structure
Ca2+ required for activity Bacillus anthracis
Mg2+ activates Bacillus anthracis

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP Bacillus anthracis
-
 3',5'-cyclic-AMP + diphosphate
-
 ?

Organism

Organism UniProt Comment Textmining
Bacillus anthracis
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP
-
 Bacillus anthracis 3',5'-cyclic-AMP + diphosphate
-
 ?
additional information development of a method for fluorimetric assay for real-time monitoring of adenylyl cyclase activity based on terbium norfloxacin, evaluation, application of radioactively labeled substrate, such as [a-32P]ATP, or fluorescently labeled antibodies, overview Bacillus anthracis ?
-
 ?

Synonyms

Synonyms Comment Organism
AC toxin
-
 Bacillus anthracis
Ca(II)- and calmodulin-dependent adenylyl cyclase edema factor
-
 Bacillus anthracis

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
25
-
 assay at Bacillus anthracis

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.4
-
 assay at Bacillus anthracis