Application | Comment | Organism |
---|---|---|
additional information | class IV AC fold is distinct from the previously described folds for class II and class III ACs | Yersinia pestis |
Crystallization (Comment) | Organism |
---|---|
at 1.9 A resolution, crystals belong to space group P212121, eight highly conserved ionic residues, E10, E12, K14, R63, K76, K111, D126, and E136 lie in the barrel core and form the likely binding sites for substrate and divalent cations. A phosphate ion bound to R63, K76, K111, and R113 near the center of the conserved cluster. AC-IV active site is relatively enriched in glutamate and features an ExE motif as its most conserved element | Yersinia pestis |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Yersinia pestis | Q7CH76 | - |
- |
Subunits | Comment | Organism |
---|---|---|
dimer | crystallography | Yersinia pestis |
Synonyms | Comment | Organism |
---|---|---|
class IV AC | - |
Yersinia pestis |
class IVadenylyl cyclase | - |
Yersinia pestis |