Activating Compound | Comment | Organism | Structure |
---|---|---|---|
HCO3- | 50 mM, 5-20fold activation in the presence of Mg2+, 3fold activation in the presence of Mn2+ | Mus musculus | |
HCO3- | 50 mM, 5-20fold activation in the presence of Mg2+, 3fold activation in the presence of Mn2+ | Rattus norvegicus |
Cloned (Comment) | Organism |
---|---|
expression of full length and truncated sAC in HEK293 cells | Mus musculus |
expression of full length and truncated sAC in HEK293 cells | Rattus norvegicus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
soluble | - |
Mus musculus | - |
- |
soluble | - |
Rattus norvegicus | - |
- |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mg2+ | 5 mM, activates sAC | Mus musculus | |
Mg2+ | 5 mM, activates sAC | Rattus norvegicus | |
Mn2+ | 5 mM, activates sAC | Mus musculus | |
Mn2+ | 5 mM, activates sAC | Rattus norvegicus |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
46000 | - |
1 * 46000, immunoblot, truncated sAC resulting from alternative splicing | Mus musculus |
46000 | - |
1 * 46000, immunoblot, truncated sAC resulting from alternative splicing | Rattus norvegicus |
49000 | - |
gel filtration, recombinant truncated sAC | Mus musculus |
49000 | - |
gel filtration, recombinant truncated sAC | Rattus norvegicus |
171000 | - |
x * 171000, immunoblot, full length sAC | Mus musculus |
171000 | - |
x * 171000, immunoblot, full length sAC | Rattus norvegicus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP | Mus musculus | - |
3',5'-cyclic AMP + diphosphate | - |
? | |
ATP | Rattus norvegicus | - |
3',5'-cyclic AMP + diphosphate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Rattus norvegicus | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP | - |
Mus musculus | 3',5'-cyclic AMP + diphosphate | - |
? | |
ATP | - |
Rattus norvegicus | 3',5'-cyclic AMP + diphosphate | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 171000, immunoblot, full length sAC | Mus musculus |
? | x * 171000, immunoblot, full length sAC | Rattus norvegicus |
monomer | 1 * 46000, immunoblot, truncated sAC resulting from alternative splicing | Mus musculus |
monomer | 1 * 46000, immunoblot, truncated sAC resulting from alternative splicing | Rattus norvegicus |
Synonyms | Comment | Organism |
---|---|---|
adenylyl cyclase | - |
Mus musculus |
adenylyl cyclase | - |
Rattus norvegicus |
sAC | - |
Mus musculus |
sAC | - |
Rattus norvegicus |
soluble adenylyl cyclase | - |
Mus musculus |
soluble adenylyl cyclase | - |
Rattus norvegicus |