Literature summary for 4.5.1.1 extracted from

Lumjuan, N.; Rajatileka, S.; Changsom, D.; Wicheer, J.; Leelapat, P.; Prapanthadara, L.A.; Somboon, P.; Lycett, G.; Ranson, H.
The role of the Aedes aegypti Epsilon glutathione transferases in conferring resistance to DDT and pyrethroid insecticides (2011), Insect Biochem. Mol. Biol., 41, 203-209.

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Inhibitors

Inhibitors	Comment	Organism	Structure
permethrin	uncompetitive inhibitor of isoform GSTE2-2	Aedes aegypti

Organism

Organism	UniProt	Comment	Textmining
Aedes aegypti	-	strains PMD-R	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
adult	-	Aedes aegypti	-
larva	-	Aedes aegypti	-
pupa	-	Aedes aegypti	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
1,1,1-trichloro-2,2-bis(4-chlorophenyl)ethane	the reaction requires the presence of GSH	Aedes aegypti	1,1-dichloro-2,2-bis(4-chlorophenyl)ethylene + HCl	-	?

Synonyms

Synonyms	Comment	Organism
DDT dehydrochlorinase	-	Aedes aegypti
GSTE2-2	isoform	Aedes aegypti
GSTE5-5	isoform	Aedes aegypti

Cofactor

Cofactor	Comment	Organism	Structure
glutathione	-	Aedes aegypti

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Release 2023.1 (January 2023)