Organism | UniProt | Comment | Textmining |
---|---|---|---|
Saccharomyces cerevisiae | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
apocytochrome c1 + heme | - |
Saccharomyces cerevisiae | holocytochrome c1 | - |
? | |
additional information | enzyme does not require the presence of putative redox protein Cyc2p, which is dedicated to the reaction of holocytochrome-c synthase, EC 4.4.1.17. A cytochrome c1 mutant with a CAPCH heme-binding site instead of the wild-type CAACH is strictly dependent upon Cyc2p for assembly. Overexpression of CC1HL, as well as mutations of the proline in the CAPCH site to H, L, S, or T residues, can bypass the absence of Cyc2p. The identity of the second intervening residue in the CXXCH motif is key in determining the holocytochrome-c synthase-dependent versus holocytochrome-c1 synthase-dependent assembly of holocytochrome c1 | Saccharomyces cerevisiae | ? | - |
? |