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Literature summary for 4.4.1.21 extracted from

  • Peixoto, R.J.; Miranda, K.R.; Ferreira, E.O.; de Paula, G.R.; Rocha, E.R.; Lobo, L.A.; Domingues, R.M.
    Production of AI-2 is mediated by the S-ribosylhomocystein lyase gene luxS in Bacteroides fragilis and Bacteroides vulgatus (2014), J. Basic Microbiol., 54, 644-649.
    View publication on PubMed
Search for more literature for 4.4.1.21

Cloned(Commentary)

Cloned (Comment) Organism
gene luxS, DNA and amino acid sequence determination and analysis, sequence comparisons Phocaeicola vulgatus
gene luxS, DNA and amino acid sequence determination and analysis, sequence comparisons, the functional luxS orthologue can complement autoinducer AI-2 production in Escherichia coli strain BL21(DE3) Bacteroides fragilis

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Bacteroides fragilis autoinducer 2 synthesis enzyme assay using Vibrio harveyi sensor strains, wild-type BB120 is a sensor mutant derived from BB120 and responds only to presence of AI-2, but not the other autoinducers from Vibrio harveyi ?
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 ?
additional information Bacteroides fragilis B3b autoinducer 2 synthesis enzyme assay using Vibrio harveyi sensor strains, wild-type BB120 is a sensor mutant derived from BB120 and responds only to presence of AI-2, but not the other autoinducers from Vibrio harveyi ?
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 ?

Organism

Organism UniProt Comment Textmining
Bacteroides fragilis
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 gene luxS
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Bacteroides fragilis B3b
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 gene luxS
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Phocaeicola vulgatus A6KYS6 gene luxS
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Phocaeicola vulgatus ATCC 8482 A6KYS6 gene luxS
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information autoinducer 2 synthesis enzyme assay using Vibrio harveyi sensor strains, wild-type BB120 is a sensor mutant derived from BB120 and responds only to presence of AI-2, but not the other autoinducers from Vibrio harveyi Bacteroides fragilis ?
-
 ?
additional information autoinducer 2 synthesis enzyme assay using Vibrio harveyi sensor strains, wild-type BB120 is a sensor mutant derived from BB120 and responds only to presence of AI-2, but not the other autoinducers from Vibrio harveyi Bacteroides fragilis B3b ?
-
 ?

General Information

General Information Comment Organism
physiological function the enzyme is required for biosynthesis of autoinducer 2, AI-2, a hormone-like molecule involved in quorum sensing, which is a cell-cell signaling mechanism based on cell density Bacteroides fragilis
physiological function the enzyme is required for biosynthesis of autoinducer 2, AI-2, a hormone-like molecule involved in quorum sensing, which is a cell-cell signaling mechanism based on cell density Phocaeicola vulgatus