Literature summary for 4.4.1.20 extracted from

Freiberg, J.J.; Tybjaerg-Hansen, A.; Sillesen, H.; Jensen, G.B.; Nordestgaard, B.G.
Promotor polymorphisms in leukotriene C4 synthase and risk of ischemic cerebrovascular disease (2008), Arterioscler. Thromb. Vasc. Biol., 28, 990-996.

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Protein Variants

Protein Variants	Comment	Organism
A444C	the mutation is associated with the risk of ischemic cerebrovascular disease	Homo sapiens
G1072A	the mutation is associated with the risk of ischemic cerebrovascular disease	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
leukotriene A4 + glutathione	-	Homo sapiens	leukotriene C4 + H2O	-	?

Synonyms

Synonyms	Comment	Organism
leukotriene C4 synthase	-	Homo sapiens
LTC4 synthase	-	Homo sapiens

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Release 2023.1 (January 2023)