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Literature summary for 4.4.1.20 extracted from
- Identification of regions of leukotriene C4 synthase which direct the enzyme to its nuclear envelope localization (2006), J. Cell. Biochem., 98, 1517-1527.
Application
| Application | Comment | Organism |
|---|---|---|
| molecular biology | the third hydrophobic region, containing a putative transmembrane helix, acts as a nuclear envelope localization signal and is involved in the homooligomerization of LTC4S | Homo sapiens |
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expression in COS-7 cells | Homo sapiens |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| endoplasmic reticulum membrane | - |
Homo sapiens | 5789 | - |
| nuclear envelope | - |
Homo sapiens | 5635 | - |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | Q16873 | - |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| HEK-293 cell | - |
Homo sapiens | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| leukotriene A4 + glutathione | - |
Homo sapiens | leukotriene C4 | - |
? |  |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| oligomer | - |
Homo sapiens |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| leukotriene C4 synthetase | - |
Homo sapiens |
| LTC4 synthase | - |
Homo sapiens |
| LTC4S | - |
Homo sapiens |
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