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Literature summary for 4.4.1.20 extracted from
- Sodium nitroprusside decreased leukotriene C4 generation by inhibiting leukotriene C4 synthase expression and activity in hepatic ischemia-reperfusion injured rats (2007), Biochem. Pharmacol., 73, 724-735.
Application
| Application | Comment | Organism |
|---|---|---|
| medicine | sodium nitroprusside inhibits leukotriene C4 synthase activity and dwonregulates the protein expression of the enzyme | Rattus norvegicus |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| sodium nitroprusside | in hepatic ischemia-reperfusion injured rats | Rattus norvegicus |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | - |
Sprague-Dawley | - |
| Rattus norvegicus Sprague-Dawley | - |
Sprague-Dawley | - |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| liver | - |
Rattus norvegicus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| leukotriene A4 + glutathione | - |
Rattus norvegicus | leukotriene C4 | - |
? | |
| leukotriene A4 + glutathione | - |
Rattus norvegicus Sprague-Dawley | leukotriene C4 | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| leukotriene C4 synthetase | - |
Rattus norvegicus |
| LTC4 synthase | - |
Rattus norvegicus |
| LTC4S | - |
Rattus norvegicus |
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