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Literature summary for 4.4.1.16 extracted from

  • Jafari, C.; Panzer, U.; Steinmetz, O.M.; Zahner, G.; Stahl, R.A.; Harendza, S.
    Enhanced expression of selenocysteine lyase in acute glomerulonephritis and its regulation by AP-1 (2006), Cell. Mol. Biol. Lett., 11, 424-437.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 4.4.1.16

Application

Application Comment Organism
medicine expression of selenocysteine lyase is higher in acute and lower in chronic glomerulonephritis, selenocysteine lyase is upregulated by IL1b in acute nephritis leading to the synthesis of selenoproteins, which act as oxygen radical scavengers and lead to the limitation and resolution of acute glomerular inflammation Rattus norvegicus

Cloned(Commentary)

Cloned (Comment) Organism
expression in Escherichia coli into the pGEM-T Easy vector for sequencing, 5’ constructs with deletions in the promoter region are subcloned into the promoterless luciferase expression vector Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
 Sprague-Dawley
-
Rattus norvegicus Sprague-Dawley
-
 Sprague-Dawley
-

Source Tissue

Source Tissue Comment Organism Textmining
kidney
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
D-cysteine + H2O
-
 Rattus norvegicus sulfide + NH3 + pyruvate
-
 ?
D-cysteine + H2O
-
 Rattus norvegicus Sprague-Dawley sulfide + NH3 + pyruvate
-
 ?

Synonyms

Synonyms Comment Organism
L-selenocysteine selenide-lyase
-
 Rattus norvegicus
SCL
-
 Rattus norvegicus
selenocysteine lyase
-
 Rattus norvegicus