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Literature summary for 4.4.1.11 extracted from
- L-Methionine-gamma-lyase, as a target to inhibit malodorous bacterial growth by trifluoromethionine (2002), Biochem. Biophys. Res. Commun., 292, 964-968.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| cloning of mgl gene | Porphyromonas gingivalis |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| L-methionine + H2O | Porphyromonas gingivalis | - |
methanethiol + NH3 + 2-oxobutanoate | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Porphyromonas gingivalis | - |
black-pigmented anaerobe strongly implicated as a major pathogen in adult periodontitis, growth of Porphyromonas gingivalis is inhibited by L-trifluoromethionine | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| L-methionine + H2O | - |
Porphyromonas gingivalis | methanethiol + NH3 + 2-oxobutanoate | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| L-methionine-alpha-deamino-gamma-mercaptomethane-lyase | - |
Porphyromonas gingivalis |
| METase | - |
Porphyromonas gingivalis |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| pyridoxal 5'-phosphate | - |
Porphyromonas gingivalis | |
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