BRENDA - Enzyme Database show
show all sequences of 4.3.3.6

Positive transcriptional control of the pyridoxal phosphate biosynthesis genes pdxST by the MocR-type regulator PdxR of Corynebacterium glutamicum ATCC 13032

Jochmann, N.; Götker, S.; Tauch, A.; Microbiology 157, 77-88 (2011)

Data extracted from this reference:

Organism
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
Corynebacterium glutamicum
-
-
-
Corynebacterium glutamicum NJ0898
-
-
-
Expression
Organism
Commentary
Expression
Corynebacterium glutamicum
expression of pdxS and pdxT is significantly reduced in the presence of pyridoxal or pyridoxal 5'-phosphate, whereas supplementing with pyridoxamine or pyridoxine shows no effect on pdxST expression
down
Corynebacterium glutamicum
the transcription regulator PdxR controls the biosynthesis of pyridoxal or pyridoxal 5'-phosphate in Corynebacterium glutamicum by activating the expression of the pyridoxal or pyridoxal 5'-phosphate synthase genes pdxST
up
General Information
General Information
Commentary
Organism
malfunction
deletion of the pdxST genes in Corynebacterium glutamicum NJ0898 results in vitamin B6 auxotrophy, which is restored by external pyridoxal, pyridoxal 5'-phosphate or pyridoxamine
Corynebacterium glutamicum
General Information (protein specific)
General Information
Commentary
Organism
malfunction
deletion of the pdxST genes in Corynebacterium glutamicum NJ0898 results in vitamin B6 auxotrophy, which is restored by external pyridoxal, pyridoxal 5'-phosphate or pyridoxamine
Corynebacterium glutamicum
Expression (protein specific)
Organism
Commentary
Expression
Corynebacterium glutamicum
expression of pdxS and pdxT is significantly reduced in the presence of pyridoxal or pyridoxal 5'-phosphate, whereas supplementing with pyridoxamine or pyridoxine shows no effect on pdxST expression
down
Corynebacterium glutamicum
the transcription regulator PdxR controls the biosynthesis of pyridoxal or pyridoxal 5'-phosphate in Corynebacterium glutamicum by activating the expression of the pyridoxal or pyridoxal 5'-phosphate synthase genes pdxST
up
Other publictions for EC 4.3.3.6
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Temperature Optimum [°C]
Temperature Range [°C]
Temperature Stability [°C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [°C] (protein specific)
Temperature Range [°C] (protein specific)
Temperature Stability [°C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
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4
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723192
Matsuura
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Pyrococcus horikoshii, Pyrococcus horikoshii OT-3
Mol. Cells
34
407-412
2012
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1
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4
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20
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2
2
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716150
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Positive transcriptional contr ...
Corynebacterium glutamicum, Corynebacterium glutamicum NJ0898
Microbiology
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2011
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1
1
2
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6
e16042
2011
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1
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8
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24
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13
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25
25
724219
Zhang
Structural insights into the c ...
Saccharomyces cerevisiae
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432
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1
6
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6
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724999
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714170
Wallner
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Bacillus subtilis
Biochemistry
48
1928-1935
2009
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10
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713758
Hanes
Trapping of a chromophoric int ...
Bacillus subtilis
Angew. Chem. Int. Ed. Engl.
47
2102-2105
2008
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716306
Hanes
13C NMR snapshots of the compl ...
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Nat. Chem. Biol.
4
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2008
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715491
Raschle
Reaction mechanism of pyridoxa ...
Bacillus subtilis
J. Biol. Chem.
282
6098-6105
2007
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1
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2
716736
Strohmeier
Structure of a bacterial pyrid ...
Bacillus subtilis
Proc. Natl. Acad. Sci. USA
103
19284-19289
2006
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715247
Burns
Reconstitution and biochemical ...
Bacillus subtilis
J. Am. Chem. Soc.
127
3682-3683
2005
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715478
Raschle
On the two components of pyrid ...
Bacillus subtilis
J. Biol. Chem.
280
32291-32300
2005
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