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Literature summary for 4.3.3.5 extracted from

  • Onaka, H.; Taniguchi, S.; Igarashi, Y.; Furumai, T.
    Characterization of the biosynthetic gene cluster of rebeccamycin from Lechevalieria aerocolonigenes ATCC 39243 (2003), Biosci. Biotechnol. Biochem., 67, 127-138.
    View publication on PubMed

Organism

Organism UniProt Comment Textmining
Lentzea aerocolonigenes
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strain ATCC 39243
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
rebeccamycin aglycone + beta-D-glucose
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Lentzea aerocolonigenes rebeccamycin + H2O
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?

General Information

General Information Comment Organism
physiological function enzyme is part of the biosynthetic gene cluster for synthesis of rebeccamycin in Lechevalieria aerocolonigenes ATCC 39243. Besides N-glycosyltransferase RebG, genes encode a monooxygenase RebC, methyltransferase RebM, transcriptional activator RebR, and halogenase RebH. A RebG gene disruption mutant produces the rebeccamycin aglycone but not rebeccamycin itself Lentzea aerocolonigenes