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Literature summary for 4.3.3.2 extracted from

  • Zhu, H.; Kercmar, P.; Wu, F.; Rajendran, C.; Sun, L.; Wang, M.; Stoeckigt, J.
    Using strictosidine synthase to prepare novel alkaloids (2015), Curr. Med. Chem., 22, 1880-1888 .
    View publication on PubMed

Application

Application Comment Organism
drug development for modern industrial drug discovery, construction of alkaloid libraries with complex scaffolds and huge backbone diversity is of paramount importance. Strategies are reported that depend on single step strictosidine synthase-catalyzed reaction. Enzyme reengineering combined with chemical methodologies is straightforward to be accessed to produce a bunch of novel alkaloids with great scaffold diversity Rauvolfia serpentina

Organism

Organism UniProt Comment Textmining
Rauvolfia serpentina P68175
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Synonyms

Synonyms Comment Organism
str
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Rauvolfia serpentina