Literature summary for 4.3.3.2 extracted from

Yamazaki, Y.; Urano, A.; Sudo, H.; Kitajima, M.; Takayama, H.; Yamazaki, M.; Aimi, N.; Saito, K.
Metabolite profiling of alkaloids and strictosidine synthase activity in camptothecin producing plants (2003), Phytochemistry, 62, 461-470.

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Inhibitors

Inhibitors	Comment	Organism	Structure
additional information	no substrate inhibition	Ophiorrhiza pumila

KM Value [mM]

KM Value [mM]	KM Value Maximum [mM]	Substrate	Comment	Organism	Structure
0.5	-	tryptamine	hairy root enzyme, 37°C	Ophiorrhiza pumila
0.9	-	secologanin	hairy root enzyme, 37°C	Ophiorrhiza pumila

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
tryptamine + secologanin	Ophiorrhiza pumila	involved in synthesis of monoterpenoid indole alkaloides	3-alpha(S)-strictosidine	-	?

Organism

Organism	UniProt	Comment	Textmining
Ophiorrhiza pumila	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
additional information	no activity in leaf and callus	Ophiorrhiza pumila	-
root	-	Ophiorrhiza pumila	-
stem	-	Ophiorrhiza pumila	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
tryptamine + secologanin	-	Ophiorrhiza pumila	3-alpha(S)-strictosidine	-	?
tryptamine + secologanin	involved in synthesis of monoterpenoid indole alkaloides	Ophiorrhiza pumila	3-alpha(S)-strictosidine	-	?

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Release 2023.1 (January 2023)