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Literature summary for 4.3.2.9 extracted from
- Selective inhibition of gamma-glutamyl-cycle enzymes by substrate analogs (1977), Proc. Natl. Acad. Sci. USA, 74, 3330-3334.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| 2-aminoglutaryl-L-1-aminobutyrate | 8 mM, 96% inhibition | Ovis aries |  |
| 5-D-glutamyl-L-2-aminobutyrate | 8 mM, 69% inhibition | Ovis aries | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Ovis aries | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| brain | - |
Ovis aries | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 5-L-glutamyl-L-alpha-aminobutyrate | - |
Ovis aries | 5-L-oxoproline + L-alpha-aminobutyrate | - |
? | |
| 5-L-glutamyl-L-amino acid | no activity with D-glutamyl-2-aminobutyrate, L-(3-methyl)glutamyl-2-aminobutyrate, 3-aminoglutaryl-2-aminobutyrate, L-5-(N-methyl)glutamyl-2-aminobutyrate, 5-(5-methyl)glutamyl-2-aminobutyrate | Ovis aries | 5-oxoproline + L-amino acid | - |
? | |
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