Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 4.3.1.6 extracted from

  • Herrmann, G.; Selmer, T.; Jessen, H.J.; Gokarn, R.R.; Selifonova, O.; Gort, S.J.; Buckel, W.
    Two beta-alanyl-CoA:ammonia lyases in Clostridium propionicum (2005), FEBS J., 272, 813-821.
    View publication on PubMed
Search for more literature for 4.3.1.6

Inhibitors

Inhibitors Comment Organism Structure
NH4+ 100 mM, 70% inhibition of NH3 elimination Anaerotignum propionicum

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.023
-
 acryloyl-CoA pH 7.5 Anaerotignum propionicum
0.21
-
 beta-alanyl-CoA pH 7.0 Anaerotignum propionicum
70
-
 NH3 pH 7.5 Anaerotignum propionicum

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
15999
-
 5 * 15999, MALDI-TOF MS Anaerotignum propionicum
75000
-
 gel filtration Anaerotignum propionicum

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Anaerotignum propionicum enzyme is induced by beta-alanine. The enzyme is needed to bind acryloyl-CoA, in order to keep the toxic free form at a very low level ?
-
 ?

Organism

Organism UniProt Comment Textmining
Anaerotignum propionicum Q6KC22 DSM 1682
-

Purification (Commentary)

Purification (Comment) Organism
-
 Anaerotignum propionicum

Source Tissue

Source Tissue Comment Organism Textmining
culture condition:beta-L-alanine-grown cell
-
 Anaerotignum propionicum
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
1033
-
-
 Anaerotignum propionicum

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
acryloyl-CoA + NH3
-
 Anaerotignum propionicum beta-alanyl-CoA
-
 r
additional information enzyme is induced by beta-alanine. The enzyme is needed to bind acryloyl-CoA, in order to keep the toxic free form at a very low level Anaerotignum propionicum ?
-
 ?

Subunits

Subunits Comment Organism
pentamer 5 * 15999, MALDI-TOF MS Anaerotignum propionicum

Synonyms

Synonyms Comment Organism
beta-alanyl-CoA:ammonia lyase 2
-
 Anaerotignum propionicum

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
25
-
 beta-alanyl-CoA pH 7.0 Anaerotignum propionicum
195
-
 acryloyl-CoA pH 7.5 Anaerotignum propionicum
301
-
 NH3 pH 7.5 Anaerotignum propionicum