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Literature summary for 4.3.1.4 extracted from
- A formiminotransferase cyclodeaminase isoform is localized to the Golgi complex and can mediate interaction of trans-Golgi network-derived vesicles with microtubules (1998), J. Biol. Chem., 273, 19602-19611.
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| cytoplasmic vesicle membrane | - |
Homo sapiens | 30659 | - |
| cytoplasmic vesicle membrane | - |
Gallus gallus | 30659 | - |
| Golgi apparatus | Golgi apparatus, formiminotransferase-cyclodeaminase enzyme complex | Homo sapiens | 5794 | - |
| Golgi apparatus | Golgi apparatus, formiminotransferase-cyclodeaminase enzyme complex | Rattus norvegicus | 5794 | - |
| Golgi apparatus | Golgi apparatus, formiminotransferase-cyclodeaminase enzyme complex | Gallus gallus | 5794 | - |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 59100 | - |
8 * 59100, calculation from sequence of amono acid, isoform of formiminotransferase-cyclodeaminase enzyme complex | Gallus gallus |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 5-formiminotetrahydrofolate | Meleagris gallopavo | - |
? | - |
? |  |
| 5-formiminotetrahydrofolate | Homo sapiens | - |
? | - |
? | |
| 5-formiminotetrahydrofolate | Rattus norvegicus | - |
? | - |
? | |
| 5-formiminotetrahydrofolate | Canis lupus familiaris | - |
? | - |
? | |
| 5-formiminotetrahydrofolate | Sus scrofa | - |
? | - |
? | |
| 5-formiminotetrahydrofolate | Gallus gallus | - |
? | - |
? | |
| 5-formiminotetrahydrofolate | Canis lupus familiaris Madin-Darby | - |
? | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Canis lupus familiaris | - |
Madin-Darby | - |
| Canis lupus familiaris Madin-Darby | - |
Madin-Darby | - |
| Gallus gallus | Q9YH58 | - |
- |
| Homo sapiens | - |
- |
- |
| Meleagris gallopavo | - |
- |
- |
| Rattus norvegicus | - |
- |
- |
| Sus scrofa | P53603 | - |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| HeLa cell | isoform of the formiminotransferase cyclodeaminase enzyme complex | Homo sapiens | - |
| hepatoma cell | - |
Homo sapiens | - |
| hepatoma cell | isoform of the formiminotransferase cyclodeaminase enzyme complex | Gallus gallus | - |
| kidney | isoform of the formiminotransferase cyclodeaminase enzyme complex | Canis lupus familiaris | - |
| liver | - |
Homo sapiens | - |
| liver | - |
Rattus norvegicus | - |
| liver | - |
Sus scrofa | - |
| liver | isoforms of the formiminotransferase cyclodeaminase enzyme complex | Meleagris gallopavo | - |
| liver | isoforms of the formiminotransferase cyclodeaminase enzyme complex | Gallus gallus | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| additional information | - |
- |
Sus scrofa |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 5-formiminotetrahydrofolate | - |
Meleagris gallopavo | 5,10-methenyltetrahydrofolate + NH3 | - |
? | |
| 5-formiminotetrahydrofolate | - |
Homo sapiens | 5,10-methenyltetrahydrofolate + NH3 | - |
? | |
| 5-formiminotetrahydrofolate | - |
Rattus norvegicus | 5,10-methenyltetrahydrofolate + NH3 | - |
? | |
| 5-formiminotetrahydrofolate | - |
Canis lupus familiaris | 5,10-methenyltetrahydrofolate + NH3 | - |
? | |
| 5-formiminotetrahydrofolate | - |
Sus scrofa | 5,10-methenyltetrahydrofolate + NH3 | - |
? | |
| 5-formiminotetrahydrofolate | - |
Gallus gallus | 5,10-methenyltetrahydrofolate + NH3 | - |
? | |
| 5-formiminotetrahydrofolate | - |
Canis lupus familiaris Madin-Darby | 5,10-methenyltetrahydrofolate + NH3 | - |
? | |
| 5-formiminotetrahydrofolate | - |
Meleagris gallopavo | ? | - |
? | |
| 5-formiminotetrahydrofolate | - |
Homo sapiens | ? | - |
? | |
| 5-formiminotetrahydrofolate | - |
Rattus norvegicus | ? | - |
? | |
| 5-formiminotetrahydrofolate | - |
Canis lupus familiaris | ? | - |
? | |
| 5-formiminotetrahydrofolate | - |
Sus scrofa | ? | - |
? | |
| 5-formiminotetrahydrofolate | - |
Gallus gallus | ? | - |
? | |
| 5-formiminotetrahydrofolate | - |
Canis lupus familiaris Madin-Darby | ? | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| octamer | - |
Rattus norvegicus |
| octamer | - |
Sus scrofa |
| octamer | 8 * 59100, calculation from sequence of amono acid, isoform of formiminotransferase-cyclodeaminase enzyme complex | Gallus gallus |
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