Literature summary for 4.3.1.3 extracted from

Hernandez, D.; Phillips, A.T.; Zon, J.
1-amino-2-imidazol-4 -ylethylphosphonic acid is a potent reversible inhibitor of Pseudomonas putida histidine ammonia-lyase (1994), Biochem. Mol. Biol. Int., 32, 189-194.

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Inhibitors

Inhibitors	Comment	Organism	Structure
1-amino-2-imidazol-4'-ylethylphosphonic acid	reversible, competitive, 1 mM: complete inhibition	Pseudomonas putida
bisulfite	10 mM, 95% loss of activity after 90 min, 0.1 mM 1-amino-2-imidazol-4'-ylethylphosphoric acid protects	Pseudomonas putida
CN-	-	Pseudomonas putida

KM Value [mM]

KM Value [mM]	KM Value Maximum [mM]	Substrate	Comment	Organism	Structure
additional information	-	additional information	-	Pseudomonas putida
1.6	-	L-histidine	pH 7	Pseudomonas putida
5.1	-	L-histidine	pH 9	Pseudomonas putida

Organism

Organism	UniProt	Comment	Textmining
Pseudomonas putida	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
L-histidine	natural substrate	Pseudomonas putida	urocanate + NH3	trans-urocanate	?

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Release 2023.1 (January 2023)