Any feedback?
Literature summary for 4.3.1.3 extracted from
- DL-alpha-Hydrazinoimidazolylpropionic acid: an irreversible inhibitor of hepatic histidine ammonia-lyase in vivo (1976), Arch. Biochem. Biophys., 177, 123-132.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| D-alpha-hydrazinoimidazolylpropionic acid | inactivates in vivo | Rattus norvegicus |  |
| DL-alpha-hydrazinoimidazolylpropionic acid | 70% irreversible inactivation in vivo | Rattus norvegicus | |
| L-alpha-hydrazinoimidazolylpropionic acid | competitive | Rattus norvegicus | |
| additional information | - |
Rattus norvegicus | |
| Nitromethane | inactivates enzyme in vivo | Rattus norvegicus | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | - |
Holtzman albion rat | - |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| partial | Rattus norvegicus |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| epidermis | stratum corneum, skin | Rattus norvegicus | - |
| liver | - |
Rattus norvegicus | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| additional information | - |
- |
Rattus norvegicus |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| L-histidine | natural substrate | Rattus norvegicus | urocanate + NH3 | - |
? | |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
