Activating Compound | Comment | Organism | Structure |
---|---|---|---|
additional information | insensitive to the allosteric activation by AMP or CMP | Entamoeba histolytica |
Cloned (Comment) | Organism |
---|---|
- |
Entamoeba histolytica |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
2-oxobutanoate | 20 mM, about 50% inhibition. Inhibition is not reversed by AMP | Entamoeba histolytica | |
glyoxylate | 20 mM, about 50% inhibition. Inhibition is not reversed by AMP | Entamoeba histolytica | |
L-Cys | competitive | Entamoeba histolytica | |
pyruvate | 20 mM, about 50% inhibition. Inhibition is not reversed by AMP | Entamoeba histolytica |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
7.3 | - |
L-Thr | pH 9.0, 37°C | Entamoeba histolytica | |
13.5 | - |
L-Ser | pH 9.0, 37°C | Entamoeba histolytica |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
45000 | - |
x * 45000, calculated | Entamoeba histolytica |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Entamoeba histolytica | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-Ser | - |
Entamoeba histolytica | pyruvate + NH3 | - |
ir | |
L-Thr | - |
Entamoeba histolytica | 2-oxobutanoate + NH3 | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 45000, calculated | Entamoeba histolytica |
Synonyms | Comment | Organism |
---|---|---|
TD1 | - |
Entamoeba histolytica |
Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
3 | - |
L-Ser | pH 9.0, 37°C | Entamoeba histolytica | |
5.2 | - |
L-Thr | pH 9.0, 37°C | Entamoeba histolytica |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
pyridoxal 5'-phosphate | - |
Entamoeba histolytica |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
1.1 | - |
L-Cys | substrate L-Ser, pH 9.0, 37°C | Entamoeba histolytica | |
2.2 | - |
L-Cys | substrate L-Thr, pH 9.0, 37°C | Entamoeba histolytica |
Organism | Comment | pI Value Maximum | pI Value |
---|---|---|---|
Entamoeba histolytica | calculated | - |
6.7 |
kcat/KM Value [1/mMs-1] | kcat/KM Value Maximum [1/mMs-1] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.2 | - |
L-Ser | pH 9.0, 37°C | Entamoeba histolytica | |
0.7 | - |
L-Thr | pH 9.0, 37°C | Entamoeba histolytica |