KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.19 | - |
D-serine | pH 8.5, 30°C | Dictyostelium discoideum |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
D-serine | Dictyostelium discoideum | the enzyme is 460fold and 1700fold more active than D-amino acid oxidase and serine racemase, respectively, in degrading D-Ser | pyruvate + NH3 | - |
? | |
D-serine | Dictyostelium discoideum AX2 | the enzyme is 460fold and 1700fold more active than D-amino acid oxidase and serine racemase, respectively, in degrading D-Ser | pyruvate + NH3 | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Dictyostelium discoideum | Q54HH2 | - |
- |
Dictyostelium discoideum AX2 | Q54HH2 | - |
- |
Purification (Comment) | Organism |
---|---|
- |
Dictyostelium discoideum |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
D-serine | - |
Dictyostelium discoideum | pyruvate + NH3 | - |
? | |
D-serine | the enzyme is 460fold and 1700fold more active than D-amino acid oxidase and serine racemase, respectively, in degrading D-Ser | Dictyostelium discoideum | pyruvate + NH3 | - |
? | |
D-serine | - |
Dictyostelium discoideum AX2 | pyruvate + NH3 | - |
? | |
D-serine | the enzyme is 460fold and 1700fold more active than D-amino acid oxidase and serine racemase, respectively, in degrading D-Ser | Dictyostelium discoideum AX2 | pyruvate + NH3 | - |
? |
Synonyms | Comment | Organism |
---|---|---|
D-Ser dehydratase | - |
Dictyostelium discoideum |
DDB_G0289463 | - |
Dictyostelium discoideum |
DSD | - |
Dictyostelium discoideum |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
30 | - |
assay at | Dictyostelium discoideum |
Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
2.6 | - |
D-serine | pH 8.5, 30°C | Dictyostelium discoideum |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
8.5 | - |
assay at | Dictyostelium discoideum |
General Information | Comment | Organism |
---|---|---|
malfunction | dsd-null cells exhibit delay in development and arrest at the early culmination stage. The efficiency of spore formation is considerably reduced in the mutant cells | Dictyostelium discoideum |
metabolism | the enzyme is 460fold and 1700fold more active than D-amino acid oxidase and serine racemase, respectively, in degrading D-Ser. D-Ser dehydrogenase is the primary enzyme responsible for D-Ser decomposition in Dictyostelium discoideum | Dictyostelium discoideum |
kcat/KM Value [1/mMs-1] | kcat/KM Value Maximum [1/mMs-1] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
14 | - |
D-serine | pH 8.5, 30°C | Dictyostelium discoideum |