KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
177 | - |
L-serine | pH 7.4, 25°C | Rattus norvegicus | |
182 | - |
L-serine | pH 7.4, 25°C, animals treated with thioacetamide for 97 days | Rattus norvegicus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
treated by oral intake of thioacetamide | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | suffering chronic injury caused by ingestion of thioacetamide. After 97 days of intake, enzyme activity is about 60% lower than in controls. No significant differences in Km-value are found, while enzyme protein level is reduced. Enzyme is localized to periportal zone of the hepatic acinus | Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-serine | - |
Rattus norvegicus | pyruvate + NH3 | - |
? |