Application | Comment | Organism |
---|---|---|
medicine | Apn1 could be used as a possible treatment strategy for attenuating or slowing down the pathogenesis of neurodegenerative diseases | Saccharomyces cerevisiae |
Cloned (Comment) | Organism |
---|---|
the yeast apurinic/apyrimidinic endonuclease gene is cloned into the pcDNA3.neo plasmid for transfection of rat RCSN-3 cells | Saccharomyces cerevisiae |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
mitochondrion | - |
Saccharomyces cerevisiae | 5739 | - |
nucleus | - |
Saccharomyces cerevisiae | 5634 | - |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
40500 | - |
Western Blots showing Apn1 expression in purified nuclear, mitochondrial extracts and whole cell lysates | Saccharomyces cerevisiae |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Saccharomyces cerevisiae | P22936 | - |
- |
Purification (Comment) | Organism |
---|---|
nuclear and mitochondrial extracts are isolated | Saccharomyces cerevisiae |
Synonyms | Comment | Organism |
---|---|---|
APN1 | - |
Saccharomyces cerevisiae |
apurinic/apyrimidinic endonuclease | - |
Saccharomyces cerevisiae |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
activity assay, oligonucleotide cleavage assay, endonuclease and 3'-phosphodiesterase activity is measured | Saccharomyces cerevisiae |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.4 | - |
activity assay, oligonucleotide cleavage assay, endonuclease and 3'-phosphodiesterase activity is measured | Saccharomyces cerevisiae |