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Literature summary for 4.2.99.18 extracted from

  • Micolas, E.; Beggs, J.M.; Haltiwanger, B.M.; Taraschi, T.F.
    A new class of DNA glycosylase/apurinic/apyrimidinic lyases that act on specific adenines in single-stranded DNA (1998), J. Biol. Chem., 273, 17216-17220.
    View publication on PubMed
Search for more literature for 4.2.99.18

Inhibitors

Inhibitors Comment Organism Structure
NaCl inhibition above 50 mM Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
DNA Homo sapiens
-
 fragments of DNA
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Reaction

Reaction Comment Organism Reaction ID
the C-O-P bond 3' to the apurinic or apyrimidinic site in DNA is broken by a beta-elimination reaction, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate mechanism Homo sapiens
a

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
DNA
-
 Homo sapiens fragments of DNA
-
 ?
DNA acts on specific adenines in single-stranded DNA Homo sapiens fragments of DNA
-
 ?
additional information gelonin, pokeweed antiviral protein and ricin belong to the family of ribosome-inactivating proteins with DNA-glycosylase/AP-lyase activities Homo sapiens ?
-
 ?