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Literature summary for 4.2.99.18 extracted from
- Human placental apurinic/apyrimidinic endonuclease. Mechanism of action (1982), J. Biol. Chem., 257, 13459-13464.
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| DNA | Homo sapiens | - |
fragments of DNA | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| placenta | - |
Homo sapiens | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| DNA | - |
Homo sapiens | fragments of DNA | - |
? | |
| DNA | cleavage of apyrimidinic DNA both 5' and 3' to the site of damage in a ratio of 60:40, respectively, even though it can cleave on both sides of an internal apyrimidinic site, it does not release deoxyribose 5-phosphate from terminal apyrimidinic sites | Homo sapiens | fragments of DNA | - |
? | |
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