Inhibitors | Comment | Organism | Structure |
---|---|---|---|
Ca2+ | complete inhibition at 2 mM | Mus musculus | |
EDTA | complete inhibition at 2 mM | Mus musculus | |
Sodium citrate | - |
Mus musculus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0000027 | - |
DNA containing apurinic site | 37°C, pH 8 | Mus musculus |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
KCl | stimulates | Mus musculus | |
KCl | optimal concentration: 50 mM,90% inhibition at 200 mM | Mus musculus | |
Mg2+ | stimulates | Mus musculus | |
Mg2+ | optimal concentration: 4-5 mM | Mus musculus | |
Mn2+ | stimulates | Mus musculus | |
Mn2+ | optimum: 4-5 mM | Mus musculus |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
28000 | - |
gel filtration | Mus musculus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
DNA | Mus musculus | - |
fragments of DNA | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Purification (Comment) | Organism |
---|---|
- |
Mus musculus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
MPC-11 cell | - |
Mus musculus | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
additional information | - |
- |
Mus musculus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
DNA | - |
Mus musculus | fragments of DNA | - |
? | |
DNA | specific for apurinic sites | Mus musculus | fragments of DNA | - |
? | |
DNA | no activity with methylated or OsO4-treated DNA | Mus musculus | fragments of DNA | - |
? | |
DNA containing apurinic site | - |
Mus musculus | ? | - |
? |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
assay at | Mus musculus |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
9.5 | - |
- |
Mus musculus |
pH Minimum | pH Maximum | Comment | Organism |
---|---|---|---|
6.5 | 10.5 | pH 6.5: about 25% of activity maximum, pH 10.5: about 20% of activity maximum | Mus musculus |