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Literature summary for 4.2.3.144 extracted from

  • Herde, M.; Gärtner, K.; Köllner, T.G.; Fode, B.; Boland, W.; Gershenzon, J.; Gatz, C.; Tholl, D.
    Identification and regulation of TPS04/GES, an Arabidopsis geranyllinalool synthase catalyzing the first step in the formation of the insect-induced volatile C16-homoterpene TMTT (2008), Plant Cell, 20, 1152-1168.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Escherichia coli Arabidopsis thaliana

Localization

Localization Comment Organism GeneOntology No. Textmining
additional information the enzyme is not localized to the plastids Arabidopsis thaliana
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-

Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+ highest activity with 10 mM Mg2+ Arabidopsis thaliana

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
geranylgeranyl diphosphate + H2O Arabidopsis thaliana the product (E,E)-geranyllinalool is a precursor to the volatile compound 4,8,12-trimethyl-1,3,7,11-tridecatetraene (TMTT) that is released by many plants in response to herbivory and may help to attract predators to combat the herbivores (E,E)-geranyllinalool + diphosphate
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?
geranylgeranyl diphosphate + H2O Arabidopsis thaliana Columbia ecotype the product (E,E)-geranyllinalool is a precursor to the volatile compound 4,8,12-trimethyl-1,3,7,11-tridecatetraene (TMTT) that is released by many plants in response to herbivory and may help to attract predators to combat the herbivores (E,E)-geranyllinalool + diphosphate
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?

Organism

Organism UniProt Comment Textmining
Arabidopsis thaliana Q93YV0
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Arabidopsis thaliana Columbia ecotype Q93YV0
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Source Tissue

Source Tissue Comment Organism Textmining
leaf
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Arabidopsis thaliana
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
geranylgeranyl diphosphate + H2O the product (E,E)-geranyllinalool is a precursor to the volatile compound 4,8,12-trimethyl-1,3,7,11-tridecatetraene (TMTT) that is released by many plants in response to herbivory and may help to attract predators to combat the herbivores Arabidopsis thaliana (E,E)-geranyllinalool + diphosphate
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?
geranylgeranyl diphosphate + H2O no activity with geranyl diphosphate or farnesyl diphosphate Arabidopsis thaliana (E,E)-geranyllinalool + diphosphate
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?
geranylgeranyl diphosphate + H2O the product (E,E)-geranyllinalool is a precursor to the volatile compound 4,8,12-trimethyl-1,3,7,11-tridecatetraene (TMTT) that is released by many plants in response to herbivory and may help to attract predators to combat the herbivores Arabidopsis thaliana Columbia ecotype (E,E)-geranyllinalool + diphosphate
-
?
geranylgeranyl diphosphate + H2O no activity with geranyl diphosphate or farnesyl diphosphate Arabidopsis thaliana Columbia ecotype (E,E)-geranyllinalool + diphosphate
-
?

Synonyms

Synonyms Comment Organism
At1g61120
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Arabidopsis thaliana
GES
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Arabidopsis thaliana
TPS04/GES
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Arabidopsis thaliana

Expression

Organism Comment Expression
Arabidopsis thaliana transcription is upregulated under conditions that induce (E,E)-geranyllinalool and 4,8,12-trimethyltrideca-1,3,7,11-tetraene synthesis, including infestation of plants with larvae of the moth Plutella xylostella and treatment with the fungal peptide alamethicin or the octadecanoid mimic coronalon. Induction requires jasmonic acid but is independent from salicylic acid or ethylene up

General Information

General Information Comment Organism
malfunction transgenic Arabidopsis lines carrying T-DNA insertions in the TPS04 locus are deficient in (E,E)-geranyllinalool and 4,8,12-trimethyl-1,3,7,11-tridecatetraene synthesis Arabidopsis thaliana