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Literature summary for 4.2.3.134 extracted from
- Degradation of O phosphohydroxylysine by rat liver. Purification of the phospho lyase (1974), J. Biol. Chem., 249, 5784-5789.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| Borohydride | inhibits the holoenzyme but no effect on the apoenzyme | Rattus norvegicus |  |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.0036 | - |
(5R)-5-phosphohydroxy-L-lysine | pH 7.4, 37°C | Rattus norvegicus | |
| 0.0105 | - |
(5R)-5-phosphohydroxy-L-lysine | pH 7.4, 37°C | Rattus norvegicus | |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 140000 | - |
gel filtration | Rattus norvegicus |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| liver | - |
Rattus norvegicus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| (5R)-5-phosphohydroxy-L-lysine + H2O | - |
Rattus norvegicus | (S)-2-amino-6-oxohexanoate + NH3 + phosphate | - |
? | |
| phosphoallohydroxy-L-lysine + H2O | - |
Rattus norvegicus | ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| phospho lyase | - |
Rattus norvegicus |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| pyridoxal 5'-phosphate | - |
Rattus norvegicus | |
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Release 2023.1 (January 2023)
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