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Literature summary for 4.2.2.20 extracted from

  • Hermel, M.; Schrage, N.F.
    Efficacy of plasmin enzymes and chondroitinase ABC in creating posterior vitreous separation in the pig: a masked, placebo-controlled in vivo study (2007), Graefes Arch. Clin. Exp. Ophthalmol., 245, 399-406.
    View publication on PubMed

Application

Application Comment Organism
medicine masked intravitreal injection of chondroitinase, human or porcine plasmin into eye of pigs. Spontaneous posterior vitreous detachment occurs more frequently in human plasmin-treated and all plasmin treated eyes than in placebo controls. Treatment with chondroitinase fails to produce an effect Proteus vulgaris

Organism

Organism UniProt Comment Textmining
Proteus vulgaris
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commercial product
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