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Literature summary for 4.2.2.1 extracted from

  • Haas, B.; Vaillancourt, K.; Bonifait, L.; Gottschalk, M.; Grenier, D.
    Hyaluronate lyase activity of Streptococcus suis serotype 2 and modulatory effects of hyaluronic acid on the bacteriums virulence properties (2015), BMC Res. Notes, 8, 722 .
    View publication on PubMedView publication on EuropePMC

Application

Application Comment Organism
medicine Streptococcus suis hyaluronate lyase does not represent a critical virulence factor in its active form. Exogenous hyaluronic acid appears to modulate several virulence determinants of the bacterium, in addition to promote inflammation Streptococcus suis

Organism

Organism UniProt Comment Textmining
Streptococcus suis
-
serotype 2
-

General Information

General Information Comment Organism
physiological function screening of 50 isolates from the three major clonal complexes found in North America (sequence types ST 1, ST25, and ST28) known to differ in their degree of virulence. All but one ST1 isolates (high virulence) are devoid of hyaluronate lyase activity whereas all ST25 (intermediate virulence) and ST28 (low virulence) isolates possess the activity Streptococcus suis