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Literature summary for 4.2.2.1 extracted from

  • King, S.J.; Allen, A.G.; Maskell, D.J.; Dowson, C.G.; Whatmore, A.M.
    Distribution, genetic diversity, and variable expression of the gene encoding hyaluronate lyase within the Streptococcus suis population (2004), J. Bacteriol., 186, 4740-4747.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 4.2.2.1

Cloned(Commentary)

Cloned (Comment) Organism
gene hyl, distribution, genetic diversity, and variable expression within the Streptococcus suis population, 309 isolates of different serotypes, geographic sources, and clinical backgrounds, overview Streptococcus suis

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Streptococcus suis the enzyme is a virulence factor of the animal pathogen, relation between enzyme activity, serotype, and disease state, overview ?
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 ?

Organism

Organism UniProt Comment Textmining
Streptococcus suis Q6H8W8 hyaluronidase fragment; gene hylA, 309 isolates of different serotypes, geographic sources, and clinical backgrounds
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Streptococcus suis Q6H8W9 hyaluronidase fragment; gene hylA, 309 isolates of different serotypes, geographic sources, and clinical backgrounds
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Streptococcus suis Q6H8X0 hyaluronidase fragment; gene hylA, 309 isolates of different serotypes, geographic sources, and clinical backgrounds
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Streptococcus suis Q6H8X1 hyaluronidase fragment; gene hylA, 309 isolates of different serotypes, geographic sources, and clinical backgrounds
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Streptococcus suis Q6H8X2 hyaluronidase fragment; gene hylA, 309 isolates of different serotypes, geographic sources, and clinical backgrounds
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Streptococcus suis Q6H8X4 hyaluronidase fragment; gene hylA, 309 isolates of different serotypes, geographic sources, and clinical backgrounds
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Streptococcus suis Q6H8X5 hyaluronidase fragment; gene hylA, 309 isolates of different serotypes, geographic sources, and clinical backgrounds
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Streptococcus suis Q6H8X6 hyaluronidase fragment; gene hylA, 309 isolates of different serotypes, geographic sources, and clinical backgrounds
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Streptococcus suis Q6H8X7 hyaluronidase fragment; gene hylA, 309 isolates of different serotypes, geographic sources, and clinical backgrounds
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Streptococcus suis Q6H8X8 hyaluronidase fragment; gene hylA, 309 isolates of different serotypes, geographic sources, and clinical backgrounds
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Streptococcus suis Q6H8Y0 hyaluronidase fragment; gene hylA, 309 isolates of different serotypes, geographic sources, and clinical backgrounds
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Streptococcus suis Q6H8Y1 hyaluronidase fragment; gene hylA, 309 isolates of different serotypes, geographic sources, and clinical backgrounds
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Streptococcus suis Q6H8Y2 hyaluronidase fragment; gene hylA, 309 isolates of different serotypes, geographic sources, and clinical backgrounds
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Streptococcus suis Q6H8Y3 hyaluronidase fragment; gene hylA, 309 isolates of different serotypes, geographic sources, and clinical backgrounds
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Streptococcus suis Q6H8Y4 hyaluronidase fragment; gene hylA, 309 isolates of different serotypes, geographic sources, and clinical backgrounds
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Streptococcus suis Q8VLQ7 hyaluronidase precursor; gene hylA, 309 isolates of different serotypes, geographic sources, and clinical backgrounds
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Streptococcus suis Q8VLQ8 hyaluronidase precursor; gene hylA, 309 isolates of different serotypes, geographic sources, and clinical backgrounds
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Reaction

Reaction Comment Organism Reaction ID
[hyaluronate]n = (4-deoxy-beta-D-gluc-4-enuronosyl)-N-acetyl-D-glucosamine-[hyaluronate]n-m-1 + 2 3-(4-deoxy-beta-D-gluc-4-enuronosyl)-N-acetyl-D-glucosamine + hyaluronate catalytic residues are Asn349, His399, and Tyr408 Streptococcus suis
a

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information the enzyme is a virulence factor of the animal pathogen, relation between enzyme activity, serotype, and disease state, overview Streptococcus suis ?
-
 ?

Synonyms

Synonyms Comment Organism
hyaluronidase
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 Streptococcus suis

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
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 assay at Streptococcus suis