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Literature summary for 4.2.2.1 extracted from

  • Oettl, M.; Hoechstetter, J.; Asen, I.; Bernhardt, G.; Buschauer, A.
    Comparative characterization of bovine testicular hyaluronidase and a hyaluronate lyase from Streptococcus agalactiae in pharmaceutical preparations (2003), Eur. J. Pharm. Sci., 18, 267-277.
    View publication on PubMed
Search for more literature for 4.2.2.1

Application

Application Comment Organism
pharmacology enzyme can be used for production of pharmaceuticals as an alternative to bovine testicular hyaluronidase, BTH, because the production of BTH is stopped due to risk of BSE Streptococcus agalactiae

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
85000
-
 x * 100000, SDS-PAGE, x * 85000, SDS-PAGE, x * 75000-50000, trypsin digested enzyme, SDS-PAGE Streptococcus agalactiae
100000
-
 x * 100000, SDS-PAGE, x * 85000, SDS-PAGE, x * 75000-50000, trypsin digested enzyme, SDS-PAGE Streptococcus agalactiae

Organism

Organism UniProt Comment Textmining
Streptococcus agalactiae
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
 activity in pharmaceutical preparations Streptococcus agalactiae

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
hyaluronan
-
 Streptococcus agalactiae 3-(4-deoxy-beta-D-gluc-4-enuronosyl)-N-acetyl-D-glucosamine
-
 ?
additional information fragments from trypsin digestion are still active, enzyme is active in SDS-PAGE Streptococcus agalactiae ?
-
 ?

Subunits

Subunits Comment Organism
? x * 100000, SDS-PAGE, x * 85000, SDS-PAGE, x * 75000-50000, trypsin digested enzyme, SDS-PAGE Streptococcus agalactiae

Synonyms

Synonyms Comment Organism
More from commercial pharmaceutical preparations Neopermease and Hylase Dessau Streptococcus agalactiae