Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 4.2.1.98 extracted from

  • Watkins, W.E.; Glass, T.L.
    Characteristics of 16-dehydroprogesterone reductase in cell extracts of the intestinal anaerobe, Eubacterium sp. strain 144 (1991), J. Steroid Biochem., 38, 257-263.
    View publication on PubMed
Search for more literature for 4.2.1.98

Inhibitors

Inhibitors Comment Organism Structure
sulfhydryl reagents
-
 Eubacterium sp.
Tris-HCl at pH above 7.0 Eubacterium sp.

Localization

Localization Comment Organism GeneOntology No. Textmining
cytoplasm 40% of the activity Eubacterium sp. 5737
-
membrane 20% of the activity Eubacterium sp. 16020
-

Organism

Organism UniProt Comment Textmining
Eubacterium sp.
-
-
-
Eubacterium sp. 144
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
16alpha-hydroxyprogesterone pyruvate or Na dithionite serve as electron donor and both reactions require methyl viologen as an electron carrier Eubacterium sp. 16,17-didehydroprogesterone + H2O
-
 ?
16alpha-hydroxyprogesterone pyruvate or Na dithionite serve as electron donor and both reactions require methyl viologen as an electron carrier Eubacterium sp. 144 16,17-didehydroprogesterone + H2O
-
 ?

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
5 8.5 activity is unaffected by pH in potassium phosphate buffer over the range pH 5.0-8.5 Eubacterium sp.