Literature summary for 4.2.1.91 extracted from

Cho, M.H.; Corea, O.R.; Yang, H.; Bedgar, D.L.; Laskar, D.D.; Anterola, A.M.; Moog-Anterola, F.A.; Hood, R.L.; Kohalmi, S.E.; Bernards, M.A.; Kang, C.; Davin, L.B.; Lewis, N.G.
Phenylalanine biosynthesis in Arabidopsis thaliana. Identification and characterization of arogenate dehydratases (2007), J. Biol. Chem., 282, 30827-30835.

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Cloned(Commentary)

Cloned (Comment)	Organism
-	Arabidopsis thaliana

KM Value [mM]

KM Value [mM]	KM Value Maximum [mM]	Substrate	Comment	Organism	Structure
0.43	-	L-arogenate	37°C	Arabidopsis thaliana
0.68	-	prephenate	37°C	Arabidopsis thaliana
0.8	-	prephenate	37°C	Arabidopsis thaliana
0.8	-	L-arogenate	37°C	Arabidopsis thaliana
1.58	-	L-arogenate	37°C	Arabidopsis thaliana
1.72	-	L-arogenate	37°C	Arabidopsis thaliana
2.44	-	prephenate	37°C	Arabidopsis thaliana
3.05	-	L-arogenate	37°C	Arabidopsis thaliana
10.08	-	L-arogenate	37°C	Arabidopsis thaliana

Organism

Organism	UniProt	Comment	Textmining
Arabidopsis thaliana	O22241	-	-
Arabidopsis thaliana	Q9FNJ8	-	-
Arabidopsis thaliana	Q9SA96	-	-
Arabidopsis thaliana	Q9SGD6	-	-
Arabidopsis thaliana	Q9SSE7	-	-
Arabidopsis thaliana	Q9ZUY3	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
L-arogenate	-	Arabidopsis thaliana	L-phenylalanine + CO2 + H2O	-	?
L-arogenate	more efficiently utilizes arogenate than prephenate	Arabidopsis thaliana	L-phenylalanine + CO2 + H2O	-	?
additional information	no activity with prephenate	Arabidopsis thaliana	?	-	?
prephenate	more efficiently utilizes arogenate than prephenate	Arabidopsis thaliana	phenylpyruvate + H2O + CO2	-	?

Synonyms

Synonyms	Comment	Organism
ADT1	-	Arabidopsis thaliana
ADT2	-	Arabidopsis thaliana
ADT3	-	Arabidopsis thaliana
ADT4	-	Arabidopsis thaliana
ADT5	-	Arabidopsis thaliana
ADT6	-	Arabidopsis thaliana
arogenate dehydratase isoform 1	-	Arabidopsis thaliana
arogenate dehydratase isoform 2	-	Arabidopsis thaliana
arogenate dehydratase isoform 3	-	Arabidopsis thaliana
arogenate dehydratase isoform 4	-	Arabidopsis thaliana
arogenate dehydratase isoform 5	-	Arabidopsis thaliana
arogenate dehydratase isoform 6	-	Arabidopsis thaliana
At1g08250	-	Arabidopsis thaliana
At1g11790	-	Arabidopsis thaliana
At2g27820	-	Arabidopsis thaliana
At3g07630	-	Arabidopsis thaliana
At3g44720	-	Arabidopsis thaliana
At5g22630	-	Arabidopsis thaliana
F25C20.4 protein	-	Arabidopsis thaliana

Turnover Number [1/s]

Turnover Number Minimum [1/s]	Turnover Number Maximum [1/s]	Substrate	Comment	Organism	Structure
0.03	-	prephenate	37°C	Arabidopsis thaliana
0.04	-	prephenate	37°C	Arabidopsis thaliana
0.16	-	prephenate	37°C	Arabidopsis thaliana
0.5	-	L-arogenate	37°C	Arabidopsis thaliana
1.1	-	L-arogenate	37°C	Arabidopsis thaliana
3.2	-	L-arogenate	37°C	Arabidopsis thaliana
4	-	L-arogenate	37°C	Arabidopsis thaliana
4.9	-	L-arogenate	37°C	Arabidopsis thaliana
6.1	-	L-arogenate	37°C	Arabidopsis thaliana

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Release 2023.1 (January 2023)