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Literature summary for 4.2.1.84 extracted from
- Optimization of crucial reaction conditions for the production of nicotinamide by nitrile hydratase using response surface methodology (2008), Appl. Biochem. Biotechnol., 151, 143-150.
Application
| Application | Comment | Organism |
|---|---|---|
| synthesis | the enzyme is useful in synthesis of compounds by hydrating biotransformations, optimization of strain cultivation and enzyme production and activity, overview | Rhodococcus erythropolis |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 3-cyanopyridine + H2O | Rhodococcus erythropolis | a step in the biosynthesis of nicotinamide, one of the important forms of vitamin B3 | nicotinamide | - |
? |  |
| 3-cyanopyridine + H2O | Rhodococcus erythropolis MTCC 1526 | a step in the biosynthesis of nicotinamide, one of the important forms of vitamin B3 | nicotinamide | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rhodococcus erythropolis | - |
- |
- |
| Rhodococcus erythropolis MTCC 1526 | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 3-cyanopyridine + H2O | - |
Rhodococcus erythropolis | nicotinamide | - |
? | |
| 3-cyanopyridine + H2O | a step in the biosynthesis of nicotinamide, one of the important forms of vitamin B3 | Rhodococcus erythropolis | nicotinamide | - |
? | |
| 3-cyanopyridine + H2O | - |
Rhodococcus erythropolis MTCC 1526 | nicotinamide | - |
? | |
| 3-cyanopyridine + H2O | a step in the biosynthesis of nicotinamide, one of the important forms of vitamin B3 | Rhodococcus erythropolis MTCC 1526 | nicotinamide | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| NHase | - |
Rhodococcus erythropolis |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 25 | - |
assay at, in vivo | Rhodococcus erythropolis |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 8 | - |
assay at, in vivo | Rhodococcus erythropolis |
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Release 2023.1 (January 2023)
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