Literature summary for 4.2.1.8 extracted from

Wichelecki, D.J.; Graff, D.C.; Al-Obaidi, N.; Almo, S.C.; Gerlt, J.A.
Identification of the In vivo Function of the High Efficiency D-Mannonate Dehydratase in Caulobacter crescentus NA1000 from the Enolase Superfamily (2014), Biochemistry, 53, 4087-4089.

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Organism

Organism	UniProt	Comment	Textmining
Caulobacter vibrioides	A0A0H3C643	-	-

Synonyms

Synonyms	Comment	Organism
D-mannonate dehydratase	-	Caulobacter vibrioides
ManD	-	Caulobacter vibrioides

Expression

Organism	Comment	Expression
Caulobacter vibrioides	expression is induced more than 1000fold when Caulobacter crescentus NA1000 is grown on D-glucuronate as a carbon source	up

General Information

General Information	Comment	Organism
malfunction	gene knockout shows no growth on D-glucoronate. Complementation of the knockout with an isopropyl beta-D-1-thiogalactopyranoside-inducible gene encoding ManD restored growth on D-glucuronate	Caulobacter vibrioides

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Release 2023.1 (January 2023)