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Literature summary for 4.2.1.51 extracted from
- Chorismate mutase: prephenate dehydratase from Acinetobacter calcoaceticus. Purification, properties and immunological cross-reactivity (1988), Eur. J. Biochem., 176, 69-79.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| L-tyrosine | 0.1 mM, 24fold activation | Acinetobacter calcoaceticus |  |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| L-phenylalanine | - |
Acinetobacter calcoaceticus | |
| m-Fluorophenylalanine | - |
Acinetobacter calcoaceticus | |
| p-Fluorophenylalanine | - |
Acinetobacter calcoaceticus | |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| potassium phosphate | 1.4-2 M, activation | Acinetobacter calcoaceticus | |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 91000 | - |
bifunctional enzyme, chorismate mutase:prephenate dehydratase, absence of L-Phe, gel filtration | Acinetobacter calcoaceticus |
| 175000 | - |
bifunctional enzyme, chorismate mutase:prephenate dehydratase, presence of L-Phe, gel filtration | Acinetobacter calcoaceticus |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| prephenate | Acinetobacter calcoaceticus | - |
? | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Acinetobacter calcoaceticus | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| bifunctional enzyme, chorismate mutase:prephenate dehydratase | Acinetobacter calcoaceticus |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| 84.2 | - |
- |
Acinetobacter calcoaceticus |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| prephenate | - |
Acinetobacter calcoaceticus | phenylpyruvate + H2O + CO2 | - |
? | |
| prephenate | - |
Acinetobacter calcoaceticus | ? | - |
? | |
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