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Literature summary for 4.2.1.49 extracted from
- Identification of alpha-ketobutyrate as the prosthetic group of urocanase from Pseudomonas putida (1970), J. Biol. Chem., 245, 528-537.
Crystallization (Commentary)
| Crystallization (Comment) | Organism |
|---|---|
- |
Pseudomonas putida |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| cyanide | KCN | Pseudomonas putida |  |
| fumarate | - |
Pseudomonas putida | |
| hydroxylamine | - |
Pseudomonas putida | |
| Imidazolepropionate | - |
Pseudomonas putida | |
| KBH4 | - |
Pseudomonas putida | |
| NaBH4 | - |
Pseudomonas putida | |
| phenylhydrazine | - |
Pseudomonas putida | |
| Semicarbazide | - |
Pseudomonas putida | |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.24 | - |
Urocanate | - |
Pseudomonas putida | |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 110000 | - |
sedimentation equilibrium centrifugation | Pseudomonas putida |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| Urocanate + H2O | Gallus gallus | - |
? | - |
? | |
| Urocanate + H2O | Felis catus | - |
? | - |
? | |
| Urocanate + H2O | Pseudomonas putida | an enzyme in the histidine catabolism | ? | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Felis catus | - |
- |
- |
| Gallus gallus | - |
- |
- |
| Pseudomonas putida | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Pseudomonas putida |
Reaction
| Reaction | Comment | Organism | Reaction ID |
|---|---|---|---|
| 3-(5-oxo-4,5-dihydro-3H-imidazol-4-yl)propanoate = urocanate + H2O | reaction mechanism | Gallus gallus | |
| 3-(5-oxo-4,5-dihydro-3H-imidazol-4-yl)propanoate = urocanate + H2O | reaction mechanism | Pseudomonas putida | |
| 3-(5-oxo-4,5-dihydro-3H-imidazol-4-yl)propanoate = urocanate + H2O | reaction mechanism | Felis catus |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| liver | - |
Gallus gallus | - |
| liver | - |
Felis catus | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| 2.16 | - |
- |
Pseudomonas putida |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| Urocanate + H2O | - |
Gallus gallus | 4,5-Dihydro-4-oxo-5-imidazolepropanoate | - |
? | |
| Urocanate + H2O | - |
Pseudomonas putida | 4,5-Dihydro-4-oxo-5-imidazolepropanoate | - |
? | |
| Urocanate + H2O | - |
Felis catus | 4,5-Dihydro-4-oxo-5-imidazolepropanoate | - |
? | |
| Urocanate + H2O | - |
Gallus gallus | ? | - |
? | |
| Urocanate + H2O | - |
Felis catus | ? | - |
? | |
| Urocanate + H2O | an enzyme in the histidine catabolism | Pseudomonas putida | ? | - |
? | |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 7.5 | - |
- |
Pseudomonas putida |
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