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Literature summary for 4.2.1.48 extracted from

  • Unkeless, J.C.; Goldman, P.
    Thermodynamic and kinetic aspects of the reaction of gamma-fluoroglutamate with D-glutamate cyclase (1971), J. Biol. Chem., 246, 2354-2359.
    View publication on PubMed
Search for more literature for 4.2.1.48

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
90
-
 5-oxo-D-proline
-
 Mus musculus
200
-
 D-glutamate
-
 Mus musculus
200
-
 cis-D-3-fluoro-2-pyrrolidone-5-carboxylate
-
 Mus musculus
1500
-
 trans-D-3-fluoro-2-pyrrolidone-5-carboxylate
-
 Mus musculus

Organism

Organism UniProt Comment Textmining
Mus musculus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Mus musculus

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
 Mus musculus
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
580
-
-
 Mus musculus

Storage Stability

Storage Stability Organism
-196°C Mus musculus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
cis-3-fluoro-2-pyrrolidone-5-carboxylate + H2O
-
 Mus musculus gamma-fluoroglutamate
-
 ?
D-glutamate
-
 Mus musculus 5-oxo-D-proline + H2O
-
 ?
erythro-gamma-fluoroglutamate
-
 Mus musculus 3-fluoro-2-pyrrolidone-5-carboxylate + H2O
-
 ?
threo-gamma-fluoroglutamate
-
 Mus musculus 3-fluoro-2-pyrrolidone-5-carboxylate + H2O
-
 ?
trans-3-fluoro-2-pyrrolidone-5-carboxylate + H2O
-
 Mus musculus gamma-fluoroglutamate
-
 ?
trans-D-3-fluoro-2-pyrrolidone-5-carboxylate + H2O
-
 Mus musculus gamma-fluoroglutamate
-
 ?