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Literature summary for 4.2.1.47 extracted from

  • Bisht, K.K.; Dudognon, C.; Chang, W.G.; Sokol, E.S.; Ramirez, A.; Smith, S.
    GDP-mannose-4,6-dehydratase is a cytosolic partner of tankyrase 1 that inhibits its poly(ADP-ribose) polymerase activity (2012), Mol. Cell. Biol., 32, 3044-3053.
    View publication on PubMedView publication on EuropePMC

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol
-
Homo sapiens 5829
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
40000
-
x * 40000, SDS-PAGE Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Subunits

Subunits Comment Organism
? x * 40000, SDS-PAGE Homo sapiens

Synonyms

Synonyms Comment Organism
GDP-D-mannose-4,6-dehydratase
-
Homo sapiens
GMD
-
Homo sapiens

General Information

General Information Comment Organism
metabolism the enzyme is required for the first step of fucose synthesis. The enzyme is a cytosolic partner of tankyrase 1 that inhibits its poly(ADP-ribose) polymerase activity and influences its stability Homo sapiens