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Literature summary for 4.2.1.47 extracted from

  • Elbein, A.D.; Heath, E.C.
    The biosynthesis of cell wall lipopolysaccharide in Escherichia coli (1965), J. Biol. Chem., 240, 1926-1931.
    View publication on PubMed
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Activating Compound

Activating Compound Comment Organism Structure
Pyridine nucleotides
-
 Escherichia coli

Inhibitors

Inhibitors Comment Organism Structure
p-chloromercuriphenylsulfonate
-
 Escherichia coli

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.55
-
 GDPmannose
-
 Escherichia coli

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
GDPmannose Escherichia coli synthesis of cell wall lipopolysaccharides ?
-
 ?

Organism

Organism UniProt Comment Textmining
Escherichia coli
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Escherichia coli

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
8.4
-
-
 Escherichia coli

Storage Stability

Storage Stability Organism
-15°C, 15 months, 40% loss of activity Escherichia coli

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
GDP-mannose
-
 Escherichia coli GDP-4-dehydro-6-deoxy-D-mannose + H2O
-
 ?
GDPmannose synthesis of cell wall lipopolysaccharides Escherichia coli ?
-
 ?

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7
-
-
 Escherichia coli