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Literature summary for 4.2.1.46 extracted from

  • Li, Z.Z.; Riegert, A.S.; Goneau, M.F.; Cunningham, A.M.; Vinogradov, E.; Li, J.; Schoenhofen, I.C.; Thoden, J.B.; Holden, H.M.; Gilbert, M.
    Characterization of the dTDP-Fuc3N and dTDP-Qui3N biosynthetic pathways in Campylobacter jejuni 81116 (2017), Glycobiology, 27, 358-369 .
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Escherichia coli Campylobacter jejuni

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
dTDP-alpha-D-glucose Campylobacter jejuni the enzyme is involved in the biosynthesis of the dTDP-3-amino-3,6-dideoxy-D-galactose and dTDP-3-amino-3,6-dideoxy-D-glucose dTDP-4-dehydro-6-deoxy-alpha-D-glucose + H2O
-
?

Organism

Organism UniProt Comment Textmining
Campylobacter jejuni Q6EB26
-
-

Purification (Commentary)

Purification (Comment) Organism
-
Campylobacter jejuni

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
dTDP-alpha-D-glucose
-
Campylobacter jejuni dTDP-4-dehydro-6-deoxy-alpha-D-glucose + H2O
-
?
dTDP-alpha-D-glucose the enzyme is involved in the biosynthesis of the dTDP-3-amino-3,6-dideoxy-D-galactose and dTDP-3-amino-3,6-dideoxy-D-glucose Campylobacter jejuni dTDP-4-dehydro-6-deoxy-alpha-D-glucose + H2O
-
?

Synonyms

Synonyms Comment Organism
RmlB
-
Campylobacter jejuni
thymidine diphosphate-glucose 4,6-dehydratase
-
Campylobacter jejuni

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
assay at Campylobacter jejuni

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.5
-
assay at Campylobacter jejuni

General Information

General Information Comment Organism
metabolism the enzyme is involved in the biosynthesis of the dTDP-3-amino-3,6-dideoxy-D-galactose and dTDP-3-amino-3,6-dideoxy-D-glucose Campylobacter jejuni