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Literature summary for 4.2.1.46 extracted from
- Identification of a dTDP-rhamnose biosynthetic pathway that oscillates with the molting cycle in Caenorhabditis elegans (2016), Biochem. J., 473, 1507-1521 .
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expression in Eschericha coli BL21(DE3) | Caenorhabditis elegans |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| dTDP-alpha-D-glucose | Caenorhabditis elegans | - |
dTDP-4-dehydro-6-deoxy-alpha-D-glucose + H2O | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Caenorhabditis elegans | Q20697 | - |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Caenorhabditis elegans |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| dTDP-alpha-D-glucose | - |
Caenorhabditis elegans | dTDP-4-dehydro-6-deoxy-alpha-D-glucose + H2O | - |
? | |
| dTDP-alpha-D-glucose | the enzyme is specifically active toward dTDP-Glc, showing little, if any, activity toward UDP-Glc and no activity toward other potential NDP-glucose substrates or toward several NDP-sugars that are abundant in Caenorhabditis elegans (e.g. GDP-Man, UDP-GlcNAc and UDPGal) | Caenorhabditis elegans | dTDP-4-dehydro-6-deoxy-alpha-D-glucose + H2O | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| rml-2 | - |
Caenorhabditis elegans |
General Information
| General Information | Comment | Organism |
|---|---|---|
| metabolism | the enzyme is involved in the dTDP-rhamnose biosynthetic pathway | Caenorhabditis elegans |
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Release 2023.1 (January 2023)
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