Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 4.2.1.46 extracted from

  • Yoo, J.C.; Han, J.M.; Sohng, J.K.
    Expression of orf7(oxi III) as dTDP-glucose 4,6-dehydratase gene cloned from Streptomyces antibioticus Tu99 and biochemical characteristics of expressed protein (1999), J. Microbiol. Biotechnol., 9, 206-212.
No PubMed abstract available
Search for more literature for 4.2.1.46

Cloned(Commentary)

Cloned (Comment) Organism
expression in Escherichia coli BL21 Streptomyces antibioticus

Inhibitors

Inhibitors Comment Organism Structure
dTDP
-
 Streptomyces antibioticus
dTTP
-
 Streptomyces antibioticus

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
38000
-
 2 * 38000, SDS-PAGE Streptomyces antibioticus

Organism

Organism UniProt Comment Textmining
Streptomyces antibioticus
-
 Tu99
-
Streptomyces antibioticus Tu99
-
 Tu99
-

Purification (Commentary)

Purification (Comment) Organism
recombinant enzyme Streptomyces antibioticus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
dTDP-glucose
-
 Streptomyces antibioticus dTDP-4-dehydro-6-deoxy-D-glucose + H2O
-
 ?
dTDP-glucose
-
 Streptomyces antibioticus Tu99 dTDP-4-dehydro-6-deoxy-D-glucose + H2O
-
 ?

Subunits

Subunits Comment Organism
dimer 2 * 38000, SDS-PAGE Streptomyces antibioticus

Cofactor

Cofactor Comment Organism Structure
NAD+ coenzyme is tightly bound to the protein Streptomyces antibioticus