Literature summary for 4.2.1.30 extracted from

Tokuyama, K.; Ohno, S.; Yoshikawa, K.; Hirasawa, T.; Tanaka, S.; Furusawa, C.; Shimizu, H.
Increased 3-hydroxypropionic acid production from glycerol, by modification of central metabolism in Escherichia coli (2014), Microb. Cell Fact., 13, 64 .

Search for more literature for 4.2.1.30

Application

Application	Comment	Organism
synthesis	7.4fold increased production of 3-hydroxypropionic acid from glycerol in the DELTAtpiA DELTAzwf DELTAyqhD Escherichia coli strain by the expression of glycerol dehydratase from Klebsiella pneumoniae and aldehyde dehydrogenase	Klebsiella pneumoniae

Cloned(Commentary)

Cloned (Comment)	Organism
expression in Escherichia coli, which does not possess the 3-hydroxypropionic acid biosynthetic pathway	Klebsiella pneumoniae

Organism

Organism	UniProt	Comment	Textmining
Klebsiella pneumoniae	Q59476 AND O08505 AND Q59475	Q59476: alpha-subunit, O08505: beta-subunit, Q59475: gamma-subunit	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
glycerol	-	Klebsiella pneumoniae	3-hydroxypropanal + H2O	-	?

General Information

General Information	Comment	Organism
metabolism	the enzyme is involved in the 3-hydroxypropionic acid biosynthetic pathway	Klebsiella pneumoniae

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)