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Literature summary for 4.2.1.30 extracted from
- Specificities of reactivating factors for adenosylcobalamin-dependent diol dehydratase and glycerol dehydratase (2000), Arch. Microbiol., 174, 81-88.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| GdrA | complex of GdrA-GdrB reactivates the enzyme | Klebsiella oxytoca | |
| GdrB | complex of GdrA-GdrB reactivates the enzyme | Klebsiella oxytoca | |
| reactivating factor for diol dehydratase | efficiently reactivates the glycerol-inactivated glycerol dehydratase in the presence of ATP, Mg2+ and adenosylcobalamin | Klebsiella oxytoca | |
| reactivating factor for diol dehydratase | reactivates the glycerol-inactivated glycerol dehydratase in the presence of ATP, Mg2+ and adenosylcobalamin with only little efficiency | Klebsiella pneumoniae |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| glycerol | - |
Klebsiella oxytoca |  |
| glycerol | - |
Klebsiella pneumoniae | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Klebsiella oxytoca | - |
- |
- |
| Klebsiella pneumoniae | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| glycerol | - |
Klebsiella pneumoniae | 3-hydroxypropanal + H2O | - |
? | |
| glycerol | - |
Klebsiella oxytoca | 3-hydroxypropanal + H2O | - |
? | |
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Release 2023.1 (January 2023)
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