Protein Variants | Comment | Organism |
---|---|---|
C450S | mutant is enzymatically inactive, glutamate auxotroph and accumulates citrate. Mutant strain exhibits overexpression of the citB promoter and accumulates high levels of aconitase protein. Mutant strain exhibits increased levels of citrate synthase protein. Mutant enzyme does not bind to the citrate synthase 5' leader RNA in vitro | Bacillus subtilis |
R741E | mutant is designed to be defective in RNA binding. Mutant strain is glutamate prototroph and accumulates citrate. Mutant strain exhibits overexpression of the citB promoter and accumulates high levels of aconitase protein. Mutant strain exhibits increased levels of citrate synthase protein. Mutant enzyme does not bind to the citrate synthase 5' leader RNA in vitro | Bacillus subtilis |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Bacillus subtilis | aconitase binds bound to the citrate synthase 5' leader RNA in vitro | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Bacillus subtilis | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | aconitase binds bound to the citrate synthase 5' leader RNA in vitro | Bacillus subtilis | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
aconitase | - |
Bacillus subtilis |
citB | - |
Bacillus subtilis |
General Information | Comment | Organism |
---|---|---|
physiological function | aconitase directly regulates citrate synthase production by interacting with the citZ transcript | Bacillus subtilis |